Equipment Purchase for Whole Genome Sequencing
Founded in 2011 as a partnership of renowned academic, medical and industry leaders, the New York Genome Center (NYGC) focuses on translating genomic research into clinical solutions for serious disease. In the not-too-distant future, scientists anticipate that every patient entering a hospital for the first time will have their genome sequenced, and the data stored in their electronic health records. Reducing the cost further is essential to spark the next wave of genomic discovery and its translation into clinical application for improved human health outcomes. This grant provides support for a revolutionary new instrument that will dramatically decrease the cost of sequencing and increase the scale and scope of research and clinical whole genome sequencing possibilities.
An Integrative Approach to the Genetics and Genomics of ALS
Founded in 2011 as a partnership of renowned academic, medical and industry leaders, the New York Genome Center (NYGC) focuses on translating genomic research into clinical solutions for serious disease. As part of this mission, NYGC is dedicated to understanding the relationship between DNA sequence variation and mechanisms for human diseases, including ALS. Funding from The Tow Foundation will support this effort by advancing the main goals of the Center for Genomics of Neurogenerative Disease at the NYGC. These goals include identifying mutations underlying neurodegenerative disease; integrating DNA sequence information with RNA sequencing data; developing a functional genomics program using mouse modes and IPS cell lines to understand the mechanistic basis of disease; create and maintain a publicly available data warehouse for ALS, DNA and RNA sequencing data; and conduct education and outreach including symposia, workshops and training.
Genetics and Genomics of ALS: Sequencing, Data Warehousing, and Analysis
For research designed to sequence both DNA and RNA samples from ALS patients to pinpoint the cellular mechanisms that have gone awry in ALS. This grant was matched by funds donated to the ALS Association from the Ice Bucket Challenge.